Highly customizable pore size and density for enhanced precision and control
Filtration is a process that happens all around us and even inside us. We enjoy drinking water that is filtered to remove solids and other impurities, and many manufacturing processes and products utilize filtration media to ensure functionality, protect critical components and reduce contamination of the environment.
Oxyphen’s Unique-Mem track-etched membranes have been used for many years by global leaders in tissue engineering and pharmaceutical research as cell culture inserts due to their precise filtration capability and hydrophilicity. In addition to cell culture, our track-etched membranes have been successfully used as infusion filters for IV drug delivery to ensure precise flow control and filtration efficiency, preventing any particles from endangering the patient.
Cell culture inserts are widely used for either cell growth for R&D applications, drug testing or used for in vitro analysis. Our track-etched membranes fit the application well, given the wide variability in membrane thickness and pore size needed to regulate the nutrient media transport to the cells that facilitates the correct growth. The inserts are widely used for either screening or distinct cell growth projects.
We offer a variety of cell culture inserts based on either a standard hanging design for three well sizes (6-, 12- and 24-well inserts) or as a customized design per customer-specific requirements. All cell culture inserts can be manufactured with a variety of Unique-Mem track-etched membranes and are bonded directly to the insert. The combination of the membrane sealing process with the Unique-Mem membrane creates a strong bond between the membrane and a perfectly smooth membrane surface, possible even for large inserts. If in-house manufacturing is preferred, Unique-Mem membranes can also be supplied as pre-treated rollstock.
Drug Delivery Infusion Filters
Infusion filters are used to reliably prevent particles from entering the human body to prevent life-threatening blood clots or to distribute drugs in a precise and controlled pattern. The filtration / retention rate can be determined by choosing the correct pore size. By selecting the best pore size, customers can determine the retention rate for small particles and determine the flow rate for the infusion solution by correlating the membrane flow rate with the priming pressure of the drug delivery solution.
Because our track-etched membranes have a highly defined pore structure, along with adjustable pore size and flow parameters, they can offer a unique solution for every infusion filter application. In addition, mounting can be done conveniently with ultrasonic welding or other assembly methods.